Tropical Journal of Pharmaceutical Research

Review Article | OPEN ACCESS

Phytochemical and Pharmacological Studies of the Genus Tacca: A Review

Jin-He Jiang^1,2, Hong-Mei Yang¹, Yi-Liang Wang², Ye-Gao Chen¹

¹Department of Chemistry; ²Department of Library, Yunnan Normal University, Kunming 650500, PR China.

For correspondence:- Ye-Gao Chen Email: jinhejiang@126.com

Received: 5 April 2013 Accepted: 6 February 2014 Published: 23 April 2014

Citation: Jiang J, Yang H, Wang Y, Chen Y. Phytochemical and Pharmacological Studies of the Genus Tacca: A Review. Trop J Pharm Res 2014; 13(4):635-648 doi: 10.4314/tjpr.v13i4.23

© 2014 The authors.
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Abstract

Tacca is an important genus comprising of approximately 15 species of the medicinal plants (Taccaceae). The plants are used in traditional medicine to relieve pains of the body and stomach, as an antidote for food poisoning as well as for their analgesic, antipyretic and anti-inflammatory activities. Chemical studies have underlined more than 120 constituents have been isolated from Tacca, including steroidals, diarylheptanoids, phenolics, flavonoids, sesquitepenoids, triterpenoids and starch. Steroidals and diarylheptanoids showed potent bioactivities, such as cytotoxic, microtubule-stabilizing, NF-κB activation and PPAR transcriptional and insecticidal activities. The starch from T. leontopetaloides and T. involucrata have high amylase content and showed potential use in food and drug system.

Keywords: Tacca, Taccalonolides, Tacca starch, Microtubule-stabilizer, Anti-cancer